Wednesday, May 1, 2013

Methylation Cycle

I'm still trying to wrap my head around this.  My poor brain isn't working well enough to get beyond "this is broken in CFS patients".

Anyway, here is a short and sweet explanation of it

Here is the lab where some CFSers are getting their DNA tested:

Mind you the people I know that have had this done are doing it on their own and not under a doctor's supervision.  Two people that I know of are tinkering with their supplements based on the results of their genetic testing.  My brain is too useless to figure this out for myself so I haven't even bothered to have the genetic testing done.  If I had a doc that could help me out with this whole thing I would be happy to have it done.

Here is the quite famous Methylation Protocol which I did try for a little while.  I might give it another go now that I'm doing better and see if there is any further improvement.  Anyway this isn't a protocol to be toyed with lightly.  As Patrick over at Quixotic ME says:

Here is Rich's famous protocol (you'll have to scroll down: the last time I checked it was the 7th post on the page)

Here is my disastrous flirtation with Rich's protocol:

My take on this is that if you are as sick as I am this isn't something to do on your own.  Have someone with a working brain help preferably a health care practitioner of some kind.  You can have a nasty potassium reaction if you miss doses of the meds or try to ween off them to fast.

EDIT:  Since Blogger won't let me comment, even on my own posts, I will answer your questions here.
Rich was an engineer whose wife has CFS/ME.  He developed the protocol and it works well for some.  I believe that it did help me but because of my bad memory I was unable to keep up the dosing schedule with any regularity.  I often missed doses entirely.  For further reading on the protocol I suggest reading the message boards on Phoenix Rising website.  Unfortunately we lost Rich not so long ago so he is no longer available to answer questions.  He was a well respected member of the CFS/ME community.

1 comment:

  1. I totally understand. I had my methylation panel done from my 23andMe results and couldn't make heads nor tails of the supplementation process.

    I guess I am also wondering if this is a 'legitimate' treatment protocol, as it does not appear to be embraced by anyone in the mainstream medical community.