Methylation Cycle

I'm still trying to wrap my head around this.  My poor brain isn't working well enough to get beyond "this is broken in CFS patients".

Anyway, here is a short and sweet explanation of it

Here is the lab where some CFSers are getting their DNA tested:
https://www.23andme.com/

Mind you the people I know that have had this done are doing it on their own and not under a doctor's supervision.  Two people that I know of are tinkering with their supplements based on the results of their genetic testing.  My brain is too useless to figure this out for myself so I haven't even bothered to have the genetic testing done.  If I had a doc that could help me out with this whole thing I would be happy to have it done.

Here is the quite famous Methylation Protocol which I did try for a little while.  I might give it another go now that I'm doing better and see if there is any further improvement.  Anyway this isn't a protocol to be toyed with lightly.  As Patrick over at Quixotic ME says:

http://quixoticmeblog.blogspot.com/2012/05/lord-of-rings-memes.html

Here is Rich's famous protocol (you'll have to scroll down: the last time I checked it was the 7th post on the page)
http://forums.phoenixrising.me/index.php?threads/simplified-methylation-protocol-revised-as-of-today.9447/

Here is my disastrous flirtation with Rich's protocol:  http://infinatedays.blogspot.com/2012/06/gaston-and-methylation-protocol.html

My take on this is that if you are as sick as I am this isn't something to do on your own.  Have someone with a working brain help preferably a health care practitioner of some kind.  You can have a nasty potassium reaction if you miss doses of the meds or try to ween off them to fast.

EDIT:  Since Blogger won't let me comment, even on my own posts, I will answer your questions here.
Rich was an engineer whose wife has CFS/ME.  He developed the protocol and it works well for some.  I believe that it did help me but because of my bad memory I was unable to keep up the dosing schedule with any regularity.  I often missed doses entirely.  For further reading on the protocol I suggest reading the message boards on Phoenix Rising website.  Unfortunately we lost Rich not so long ago so he is no longer available to answer questions.  He was a well respected member of the CFS/ME community.